Síntese de Sulfetos e Selenetos Graxos Quirais derivados do Óleo de Mamona.

Abstract

In order to contemplate some of the principles of Green Chemistry, in this study new organochacogen compounds derived from renewable sources, such as castor oil were synthesized. The alkyl 12-organylchalcogenoctadec-9-enoates were obtained starting from a transesterification reaction of castor oil 1, followed by tosylation of hydroxyl group of methyl ricinoleate 2 and subsequent nucleophilic substitution with chalcogenolate anions affording fatty chiral sulfides 5 and selenides 7 (Scheme 1). This proved to be efficient synthetic route for the synthesis of fatty chiral sulfides and selenides with good yields with potential application in biological studies.