Perfil energético de éguas gestantes e seus neonatos

Abstract

Pregnancy and the neonatal period mark important stages in the lives of beings. The study of metabolic changes that occur during these periods is important to understand, predict and control possible pathologies. This thesis aimed to determine and evaluate the energy profile of pregnant mares and their newborns, to understand the mare-foal relationship. In the first study, blood was collected from native mares in the periods prior to parturition, in addition to measurements made regarding weight gain, either by monitoring the different ways of measuring weight, or by measuring body and metabolic fat. In the present study, these variables correlated (p < 0,0001) and there was an increase in the total blood cholesterol levels of the mares on the day of delivery (p = 0,0016). Thus, continuing the study, the second article was developed where native peripartum mares and their newborns had their blood collected and evaluated for levels of total cholesterol, triglycerides, LDL (low-density lipoprotein) and HDL (high-density lipoprotein). In addition, in the foals, blood lactate and glucose levels were measured. A real increase in cholesterol was observed in mares on the day of parturition, with a return of values in the immediate postpartum period (p=0.02). Correlation was found between the total cholesterol levels of mares and foals at the time of parturition (r = 0,457, P = 0,011). In addition, there was a correlation between total cholesterol and triglycerides in the mare and total cholesterol in the foal, and total cholesterol in the mare and LDL in the foal. Our results demonstrate how the lipid profile of neonates fluctuates and can be interfered with in various ways. Pregnant mare showed an increase in cholesterol levels at day of foaling. Furthermore, our study demonstrated the relationship between total cholesterol and triglycerides in the mare and total cholesterol in the newborn foal, and total cholesterol in the mare and LDL in the newborn foal. There was an inversely proportional correlation between the levels of HDL and LDL levels in the blood of the newborn foal, which influenced the maintenance of the levels of other components, such as glucose, which correlates with lactate on the day of foaling, which demonstrates that we must be attentive to the evaluation of the moment of these components.