Análise epidemiológica da dengue na Amazônia Legal Brasileira 2001-2021

Abstract

Dengue is one of the main existing urban arboviruses, transmitted by mosquitoes of the genus Aedes. It is characterized as a serious public health problem, especially in countries with favorable environmental conditions for its dispersion, growth and proliferation of the vector. This dissertation aims to characterize the changes that occurred in the space-time dynamics of Dengue in the 772 municipalities that comprise the nine states of the Brazilian Legal Amazon in the period from 2001 to 2021. For the development of the study, databases generated by the National Disease System were analyzed. of Notification (SINAN). During the studied period, approximately 1,344,950 cases of the disease were reported, of which 863 cases evolved to death. The distribution of cases varied over the study period. According to the GAM analysis, an increase in the risk of occurrence of the disease was observed in the Amazon region from 2005 onwards, with a peak in 2010, followed by a decrease in risk until 2017, between 2018 and 2021, the risk of the disease returned to increase in the region. A significant association of socioeconomic and environmental variables with Dengue cases in the region during the study period was verified. This dissertation is composed of two scientific articles referring to the epidemiological analysis of Dengue in the Brazilian Amazon region.