Estudo retrospectivo de candidíase oral, isolamento e identificação de variáveis associadas com candidíase atrófica crônica

Abstract

The treatment of choice for chronic atrophic candidiasis (denture stomatitis) is the use of antifungals, usually in topical form but also systemic therapy may be required in some cases. Be systemic or topical form, prolonged and repeated use of antifungal contributes to the development of resistant strains. This study aimed to survey the demographic and clinical profile of patients diagnosed with candidiasis and treated in the Mouth Disease Diagnostic Center (CDDB), Faculty of Dentistry of Pelotas (FO / UFPel) in 1997 to 2014 and isolate, identify and evaluate the antifungal susceptibility isolated yeast oral candidiasis patients diagnosed with chronic atrophic (denture stomatitis) showing resistance to treatment with the use of conventional antifungal agents. We evaluated the records of patients seen in the Service (CDDB) for 18 years. Variables as race, gender, age, systemic diseases, type and location of candidiasis symptoms and harmful habits were collected. Furthermore, the collection and isolation of Candida from patients with a clinical diagnosis of chronic atrophic candidiasis was performed. Later, species identification and evaluation of their antifungal resistance through automated method Vitek 2 (bioMérieux) was performed. Statistical analysis was performed using the chi-square test and Poison Regression. The significance level used in the tests was 5% (p 0.05). The software being used was the STATA 13.1.