Síntese de bis-arilseleno alquenos utilizando KF/Al2O3 e PEG-400.

Abstract

In this paper bis-arylselene alkenes were synthesized using KF/Al2O3 as a base and PEG-400 as a solvent (Scheme 1). The methodology proposed is based on the principles of Green Chemistry, in which by a one-pot procedure from terminal alkynes (1) and diaryl diselenides (2), the corresponding bisselene alkenes of configuration Z (3) were obtained in good yields for eight examples, with aromatic and aliphatic substituents. Moreover, it was possible to reduce the reaction time by using microwave irradiation and reuse the KF/Al2O3/PEG-400 system without prior treatment while maintaining its activity.