Nível socioeconômico ao longo da vida, adiposidade e marcadores metabólicos em adultos jovens

Abstract

Brazil is economically unequal country and considered the tenth most unequal country in the world in the year 2015. With few exceptions, the occurrence of various diseases and health problems is aggravated among social groups that are living in socially disadvantaged situations, i.e., among the poorest, the ethnic minority groups or groups that suffer discrimination. The poorest countries have worse health conditions when compared to the richest ones. There is evidence that both adverse socioeconomic conditions early in life and in adult life may lead to increased accumulation of adipose tissue and alter inflammatory status. However, the relationship between the socioeconomic status and the subclinical form of chronic diseases, which is essential in terms of prevention, is poorly investigated. In order to assess the relationship between socioeconomic status and adiposity and metabolic markers (HDL and LDL) in young adults belonging to the 1993 Pelotas (Brazil) birth cohort, we tested three hypotheses of cumulative and dynamic nature of socioeconomic status (accumulation, critical period and social mobility) throughout life. The present thesis also investigates the mediation of adiposity in the association between socioeconomic status throughout life and metabolic markers in adult life.