Líquido Iônico [bmim][SeO2(OMe)] como solvente reciclável na síntese livre de catalisador de 3-selenilindóis

Abstract

In this work, it was developed a cleaner synthetic methodology for the preparation of 3-selenylindoles 3a-i, through indole electrophilic substitution reaction using the ionic liquid [bmim][SeO2(OMe)] as solvent without the necessity of use catalysts and additives, the products were obtained in moderate to good yields. Additionally, a study on the recovery and reuse of [bmim][SeO2(OMe)] was performed. We observed a good level of efficiency in four reuse cycles, reducing the emission of waste and contemplating the principles of Green Chemistry.