Síntese de selanilalquinos via ativação Csp-H Catalisada por nitrato de prata

Abstract

In this present work, we describe a simple methodology for the synthesis of different alkynyl selenides 3a-p through reactions between terminal alkynes 1a-i and diorganyl diselenides 2a-f in the presence of silver nitrate (AgNO3) as catalyst with yields ranging from 40 to 98%. This methodology presents advantages over the previously described methods since it does not require the use of base and occurs under the temperature of 25 °C. In addition, this discovery opens new possibilities for the further development of methods employing the use of silver salts as a catalyst in the chemistry of organic selenium compounds.