Grafeno funcionalizado com nanopartículas de ferro: sensor eletroquímico e enzimático

Abstract

Glucose sensors have become one of the most importante instruments for biological analysis. The importance of non-invasive mechanisms for determining glucose is in the use human samples without the least discomfort. These sensors can assist in training athletes and prescribing exercises for the general population, especially during the pandemic. The reduced graphene oxide (GOr) is the most importante among chemically modified graphenes. The use of reduced graphene oxide (GOr) functionalized with other metals can be a viable alternative in the construction of electrochemical sensors. The objective of this study was to develop a platform with GOr functionalized with iron (GOrFe) for application as an electrochemical biosensor for glucose detection. The device was tested electrochemically by cyclic voltammetry (VC) and amperometry. The data revealed a good VC electrochemical sensitivity for VC in response to different glucose concentration. The analytical curve demonstrated a good response in terms of detection limit (LD) 8.98μM and 8.05μM, and quantification limit (LQ) 29.94μM and 26.82μM for the analyte present in phosphate buffer (PBS) and synthetic sweat, respectively. In conclusion, GOrFe can be a good alternative in the development of an electrochemical biosensor for glucose detection.