Efeito da dieta de cafeteria em ratos submetidos ao estresse crônico variado: análise de parâmetros bioquímicos e comportamentais

Abstract

Obesity is defined as an accumulation of fat in the body, caused by a sedentary lifestyle and consumption of high-calorie foods. Diseases related to overweight are considered one of the most serious problems of public health worldwide, associated with risk of diabetes and cardiovascular disease and certain cancers. Stress has also been mentioned as a problem of modern society that causes emotional and physiological disorders. In the last decades has been the increasing number of stress-related, overweight and obesity, associated with increased consumption of energy- dense foods. The object of study to evaluate the effects of a cafeteria diet associated with chronic varied stress (CVS) in biochemical parameters, deposits of body fat and behavioral. Stress Group (S) - standard chow and stress; cafeteria diet group without stress (D) and diet + stress group (SD) standard model without stress control group rats (C): Fourt Wistar rats were divided into four groups used). The animals were submitted to the CVS for 40 days on alternate days and times. The parameters of anxiety assessed by Plus Maze showed that the diet was able to reverse or ameliorate the effects of stress. Locomotors activity, assessed by the Open Field Test was not altered by diet or by stress. The memory assessed by the Object Recognition Test has changed, neither by diet nor by stress. Animals in group E had lower weight gain, diet and offset the effect of stress in relation to weight gain in animals fed cafeteria diet and CVS. There was an increase in liver weight and adipose tissues (subcutaneous and abdominal) of animals that received the cafeteria diet, but not undergoing CVS. Serum glucose, triglycerides, total cholesterol, HDL- Cholesterol, lipase, were measured, but not changed significant.